This 140-mile byway spans the section of the Cascade Loop from Twisp in the Methow Valley to Sedro-Woolley, in the Skagit Valley. Expect the landscape and environment to change radically as you pass through classic Methow Valley Country (think spaghetti westerns and real-life cowboys and cowgirls) and ascend into the North Cascades National Park, winding your way through jagged mountain peaks, rocky spires, rushing waterfalls and alpine glaciers (the North Cascades are often referred to as the "North American Alps) and then into the green, pastoral Skagit Valley. Don't forget to stop at Ross and Diablo Dam Overlooks for iconic photo ops!